Abstract
Basal cell carcinoma BCC frequently occurs at skin of nose, but primary involvement of anterior nares and nasal floor seems to be very rare. A 62-year-old man is presented with an ulcerated plaque on the right nostril which developed 10 years ago and enlarged in time. He denied excessive sun-exposure or trauma to this area. The history was negative for immunosuppressive diseases or therapies. On dermatologic examination, small, pinkish, waxy papules composing a rolled edge were seen on the base and lateral walls of the right nostril. The lesion was extending into nasal cavity, with an indistinct border. Total body skin examination did not show any findings for syndromic BCC. Histopathologic examination revealed a solid type of BCC, involving both skin and mucosal surfaces of the nostril. In several large case series of nasal BCC, involvement of nostrils was exceptionally rare. The cause of this infrequency is not known exactly yet, but is likely to be affected by a relatively low exposure of ultraviolet irradiation and undefined factors.
References
- Mora RG, Robins P. Basal-cell carcinomas in the center of the face: special diagnostic, prognostic, and therapeutic considerations J Dermatol Surg Oncol. 1978; 4: 315-21.
- Heckmann M, Zogelmeier F, Konz B. Frequency of facial basal cell carcinoma does not correlate with site-specifi c UV exposure. Arch Dermatol 2002; 138: 1494-7.
- Hatano Y, Terashi H, Kurata S, Asada Y, Shibuya H, Tanaka A, Tada H, Fujiwara s, et al. Invasion of the lacrimal system by basal cell carcinoma. Dermatol Surg 1999; 25: 823-6.
- Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol 2002; 147: 41-7.
- Bonvallot T, Raulo Y, Zeller J, Faivre JM, Horn G, Baruch J. Basal cell carcinoma of the nose Ann Dermatol Venereol 1993; 120: 209-14.
- Nordin P, Larkö O, Stenquist B. Five-year results of curettage-cryosurgery of selected large primary basal cell carcinomas on the nose: an alternative treatment in a geographical area underserved by Mohs’ surgery. Br J Dermatol 1997; 136: 180-3.
- Del Rosario RN, Barr RJ, Jensen JL, Cantos KA. Basal cell carcinoma of the buccal mucosa. Am J Dermatopathol 2001; 23: 203-5.
- Lindgren G, Diff ey BL, Larkö O. Basal cell carcinoma of the eyelids and solar ultraviolet radiation exposure. Br J Ophthalmol 1998; 82: 1412-5.
- Brooke RC, Newbold SA, Telfer NR, Griffi ths CE. Discordance between facial wrinkling and the presence of basal cell carcinoma. Arch Dermatol 2001; 137: 751-4.
Abstract
Bazal hücreli karsinom BHK burunda sık yerleşir, ancak tümörün burun boşluğu tabanı ve burun deliklerinden başlaması çok nadirdir. Altmış iki yaşında bir erkek hasta sağ burun deliğinde 10 yıl önce başlayıp ilerleyen ülserli bir plak nedeniyle başvurdu. Bu bölgeye travma veya aşırı ve uzun süreli güneş teması belirtilmedi. Öyküde immünsüpresyona yol açacak herhangi bir hastalık veya tedavi de tanımlanmadı. Deri muayenesinde sağ burun deliğinin alt ve yan duvarlarında deri renginde ve pembemsi küçük papüllerin oluşturduğu, kabarık kenarlı, ortası yüzeyel olarak ülserleşmiş bir plak saptandı. Lezyon sınırları tam olarak belirlenememekle beraber burun boşluğuna doğru uzanım gösteriyordu. Tüm vücut deri muayenesinde nevoid BHK sendromuna ait herhangi bir bulguya rastlanmadı. Histopatolojik incelemede deri ve mukozayı tutan solid tipte BHK saptandı. Burunda yerleşen BHK’u ele alan geniş olgu çalışmalarda burun deliklerinin tutulumuna çok ender rastlandığı görülmektedir. Bu durumun nedeni tam olarak bilinmemektedir, ancak göreceli olarak düşük ultraviyole ışık ve henüz tam olarak tanımlanmamış başka faktörlerin etkili olması muhtemeldir
References
- Mora RG, Robins P. Basal-cell carcinomas in the center of the face: special diagnostic, prognostic, and therapeutic considerations J Dermatol Surg Oncol. 1978; 4: 315-21.
- Heckmann M, Zogelmeier F, Konz B. Frequency of facial basal cell carcinoma does not correlate with site-specifi c UV exposure. Arch Dermatol 2002; 138: 1494-7.
- Hatano Y, Terashi H, Kurata S, Asada Y, Shibuya H, Tanaka A, Tada H, Fujiwara s, et al. Invasion of the lacrimal system by basal cell carcinoma. Dermatol Surg 1999; 25: 823-6.
- Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol 2002; 147: 41-7.
- Bonvallot T, Raulo Y, Zeller J, Faivre JM, Horn G, Baruch J. Basal cell carcinoma of the nose Ann Dermatol Venereol 1993; 120: 209-14.
- Nordin P, Larkö O, Stenquist B. Five-year results of curettage-cryosurgery of selected large primary basal cell carcinomas on the nose: an alternative treatment in a geographical area underserved by Mohs’ surgery. Br J Dermatol 1997; 136: 180-3.
- Del Rosario RN, Barr RJ, Jensen JL, Cantos KA. Basal cell carcinoma of the buccal mucosa. Am J Dermatopathol 2001; 23: 203-5.
- Lindgren G, Diff ey BL, Larkö O. Basal cell carcinoma of the eyelids and solar ultraviolet radiation exposure. Br J Ophthalmol 1998; 82: 1412-5.
- Brooke RC, Newbold SA, Telfer NR, Griffi ths CE. Discordance between facial wrinkling and the presence of basal cell carcinoma. Arch Dermatol 2001; 137: 751-4.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | March 1, 2011 |
| Published in Issue | Year 2011Issue: 1 |