Upper Gastrointestinal Disorders Among Dialysis Patients

Şafak Kızıltaş; Sevgi Şahin

EN TR

Upper Gastrointestinal Disorders Among Dialysis Patients

Abstract

The prevalence of co-morbid gastrointestinal symptoms is high in dialysis patients, and dyspeptic symptoms, such as nausea, vomiting, and epigastric burning are the most common symptoms. Upper gastrointestinal disorders e.g., peptic ulcer disease and gastroparesis underlie most of these symptoms, while less common but severe complications are also likely that include gastrointestinal bleeding from gastric antral vascular ectasia, erosions or ulcers. Incidence of gastrointestinal disorders is considered to increase with the duration of renal failure, independent of dialysis modality. While uremia and dialysis have been linked to an increased risk of gastrointestinal tract lesions, pathogenesis of gastrointestinal dysfunction in end-stage renal disease is considered to be multifactorial and has not yet been clarified. In addition, conflicting data exist on the association of renal dysfunction with gastrointestinal disorders, and there are no explicit guidelines for the management of co-morbid gastrointestinal problems in patients with concomitant renal failure. Herein, we review the common upper gastrointestinal disorders that occur among dialysis patients, with an emphasis on prevalence, pathogenesis and diagnostic strategies

Keywords

End-stage renal disease,peritoneal dialysis,hemodialysis,upper gastrointestinal tract,pathogenesis

DIYALIZ HASTALARINDA ÜST GASTROINTESTINAL SISTEM HASTALIKLARI

Öz

Diyaliz hastalarında komorbid gastrointestinal semptomlar yüksek prevalansa sahiptir. Bulantı, kusma ve mide yanması gibi dispeptik semptomlar en yaygın gastrointestinal semptomlardır. Üst gastrointestinal sistem hastalıkları örn., peptic ülser hastalığı ve gastroparezi bu semptomların önemli nedenleri arasındadır. Ek olarak gastrik antral vasküler ektaziye bağlı kanama erozyon veya ülser gelişimi gibi nadir ancak şiddetli komplikasyonlar da gözlenebilmektedir. Gastrointestinal hastalık insidansının, diyaliz türünden bağımsız ve renal yetmezlik süresi ile orantılı olarak artış gösterdiği kabul edilmektedir. Üremi ve diyaliz gastrointestinal sistem lezyon gelişimi için bir risk faktörü olmakla birlikte, son dönem renal hastalığa bağlı gastrointestinal fonksiyon bozukluğu gelişimi çok faktörlü ve henüz netlik kazanmamış bir patogeneze sahiptir. Ek olarak, renal fonksiyon bozukluğu ve gastrointestinal bozukluklar arasındaki ilişkiye dair çelişkili veriler mevcut olup, renal yetmezlik zemininde gelişen gastrointestinal hastalıkların yönetimine dair özgül kılavuzlar bulunmamaktadır. Bu derleme makalede, diyaliz hastalarında sık gözlenen üst gastrointestinal sistem hastalıkları prevalans, patogenez ve tanısal yaklaşımlar bazında sunulmaktadır

Anahtar Kelimeler

Son dönem renal hastalık,periton diyalizi,hemodiyaliz,üst gastrointestinal sistem,patogenez

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Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Şafak Kızıltaş

Sevgi Şahin

Publication Date

June 1, 2019

Submission Date

-

Acceptance Date

-

Published in Issue

Year 2019 Number: 2

IZ

https://izlik.org/JA35FD33NG

Cite

RIS / Bibtex

EndNote

Kızıltaş Ş, Şahin S (June 1, 2019) Upper Gastrointestinal Disorders Among Dialysis Patients. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 2 135–141.